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Subsequent yeast studies helped further characterize this membrane-associated toxicity: wt human αS expression in yeast (which lack an αS gene) led to vesicle clustering/aggregation 67,68 and vesicle-trafficking defects

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It was also notable that the amount of GGP3 transcript was significantly higher in mature leaves than in young leaves at the vegetative stage (Figure 2a), and a similar tendency was observed for GGP1 ( P 50%) in wild‐type plants at normal conditions were excluded